RAPAMUNE: First Food And Drug Administration (FDA) Approved Lymphangioleiomyomatosis Treatment Medication By Pfizer’s

Pfizer announced that the United States FDA has approved its RAPAMUNE (sirolimus), which is the first LMA medication to be approved by the body as a treatment to Lymphangioleiomyomatosis. LMA is a unique and rare disease affecting the lymphatic system, lungs, and the kidneys.

The medication for the rare disease helps in stabilizing the lungs functioning. Pfizer reveals the success was a result of collaboration between the firm, FDA, and the LAM foundation. RAPAMUNE is approved in the United States as an immunosuppressive agent used during kidney transplants in patients who are above 13 years old.

daylightRAPAMUNE medication comes as a relief to the 800 plus patients in the US suffering from this rare and fatal complication. LAM leads to the development of unpredicted growth of muscles in the lungs. The muscle growth interferes with oxygen transportation in the body

RAPAMUNE got the FDA approval after the MILES trial results, which were done, on 89 patients who were suffering from slight lung defects. The results for those treated with the medication over a period of one year showed they achieved lung stabilization. Scientists term the approval of the Pfizer medicine as a breakthrough and major relief to the LAM patients.

Safety information

RAPAMUNE has not come out safe to people who earlier had lung or liver transplant. If used after any of the two transplants, the users may result in serious complications and eventually cause death. Any patient who had liver or lung transplant should only take the medication after consulting their personal doctor.

Any patient who is allergic to any of its ingredients or sirolimus should not take RAPAMUNE. Allergic symptoms of the medication ingredients include swelling of the eye, face or mouth, chest pains, throat tightness, a dizziness feeling and skin peeling.

If the patient is suffering from any of the following complications they should notify their personal doctor before they start the medication; skin cancer, high cholesterol, pregnancy or breastfeeding. Care should be taken when a patient is taking RAPAMUNE while they have other medication at the same time.

Some of the associated side effects include, hands swelling, breathing difficulties, wounds may take long to heal, increased level of cholesterol, increased protein content in the urine, diarrhea, stomach pains, sore throat, headache, nausea and shortness of breathing.

Other side effects include, blood clotting problems and wound opening, high blood pressure, pains in the joints and stomach, fever, infection in the urine track, low number of platelets in the blood and sometimes the kidney functioning may be slowed.